The nasopharyngeal epithelium is very prone to pathogenic an infection. Greater than 95% of nasopharyngeal carcinomas (NPCs) are Epstein-Barr virus (EBV)-associated epithelial cancers densely infiltrated with EBV-free lymphocytes. It stays unknown whether or not the immune modulating results of concurrent chemoradiotherapy (CCRT) on the tumor-infiltrating T-cell priming in opposition to EBV, tumor-associated antigens, and/or neoantigens can elicit systemic anti-tumor immunity and reduce recurrence or distant metastasis.
Utilizing matched EBV-associated NPCs, nasopharyngeal mucosal tissues, and longitudinal serial peripheral blood samples, we explored the spatiotemporal and quantitative modifications in enlargement and contraction of intratumoral T-cell clonotypes (ITCs) in peripheral blood samples from earlier than, throughout, and after CCRT.
The pre-treatment nasopharyngeal ITC repertoire contained distinctive mucosa-resident and generally system-shared T-cell receptors, portraying an individualized tumor-associated and/or metagenomic panorama. We discovered that the long-term disease-free sufferers had considerably extra sturdy distinctive mucosa-resident ITCs that migrated into and expanded within the peripheral blood after CCRT than within the sufferers with recurrence or distant metastasis.
Nonetheless, the system-shared productive ITC TCRs particular to the widespread viruses, akin to EBV, cytomegalovirus, and influenzaA, in all of the sufferers with and with out recurrence demonstrated virtually no enlargement after CCRT. Thus, these findings underline the significance of figuring out the impression of distinctive intratumoral immune responses, mirrored within the peripheral blood, on illness prognosis after therapy and problem of mechanistically understanding the widespread systemic immune evasion of EBV in NPC sufferers.
We examine the structural and orientational variability of the membrane-embedded T cell receptor (TCR) – CD3 complicated in intensive atomistic molecular dynamics simulations based mostly on the current cryo-EM construction decided by Dong et al. (2019). We discover that the TCR extracellular (EC) area is very variable in its orientation by attaining tilt angles relative to the membrane regular that vary from 15° to 55°.
The lean angle of the TCR EC area is each coupled to a rotation of the area and to attribute modifications all through the TCR – CD3 complicated, particularly within the EC interactions of the C_ FG loop of the TCR, in addition to within the orientation of transmembrane helices. The concerted motions of the membrane-embedded TCR – CD3 complicated revealed in our simulations present atomistic insights on conformational modifications of the complicated in response to tilt-inducing forces on antigen-bound TCRs.
A mix of broadly-reactive and pathogen-selected Vγ4 Vδ1 T cell receptors confer broad bacterial reactivity of resident reminiscence γδ T cells
Though murine γδ T cells are largely thought of innate immune cells, they’ve lately been reported to type long-lived reminiscence populations. A lot stays unknown in regards to the biology and specificity of reminiscence γδ T cells. Right here, we interrogated intestinal reminiscence Vγ4 Vδ1 T cells generated after foodborne Listeria monocytogenes (Lm) an infection to uncover an unanticipated complexity within the specificity of those cells.
Deep TCR sequencing revealed {that a} subset of non-canonical Vδ1 clones are chosen by Lm an infection, per antigen-specific clonal enlargement. Ex vivo stimulations and in vivo heterologous problem infections with various pathogenic micro organism revealed that Lm-elicited reminiscence Vγ4 Vδ1 T cells are broadly reactive.
The Vγ4 Vδ1 T cell recall response to Lm, Salmonella enterica serovar Typhimurium (STm) and Citrobacter rodentium was largely mediated by the γδTCR as internalizing the γδTCR prevented T cell enlargement. Each broadly-reactive canonical and pathogen-selected non-canonical Vδ1 clones contributed to reminiscence responses to Lm and STm.
Curiously, some non-canonical γδ T cell clones chosen by Lm an infection additionally responded after STm an infection, suggesting some stage of cross-reactivity. These findings underscore the promiscuous nature of reminiscence γδ T cells and counsel that pathogen-elicited reminiscence γδ T cells are potential targets for broad-spectrum anti-infective vaccines.
Hierarchy of signaling thresholds downstream of the T cell receptor and the Tec kinase ITOk
The energy of peptide:MHC interactions with the T cell receptor (TCR) is correlated with the time to first cell division, the relative scale of the effector cell response, and the graded expression of activation-associated proteins like IRF4. To manage T cell activation programming, the TCR and the TCR proximal interleukin-2-inducible T cell kinase (ITK) concurrently set off many biochemically separate signaling cascades.
T cells missing ITK exhibit selective impairments in effector T cell responses after activation, however below the strongest signaling circumstances, ITK exercise is dispensable. To achieve perception into whether or not TCR sign energy and ITK exercise tune noticed graded gene expression by the unequal activation of distinct signaling pathways, we examined Erk1/2 phosphorylation or nuclear issue of activated T cells (NFAT) and nuclear issue (NF)-κB translocation in naïve OT-I CD8+ cell nuclei.
We noticed the constant digital activation of NFAT1 and Erk1/2, however NF-κB displayed dynamic, graded activation in response to variation in TCR sign energy, tunable by therapy with an ITK inhibitor. Inhibitor-treated cells confirmed the dampened induction of AP-1 elements Fos and Fosb, NF-κB response gene transcripts, and survival issue Il2 transcripts. ATAC sequencing evaluation additionally revealed that genomic areas most delicate to ITK inhibition had been enriched for NF-κB and AP-1 motifs.
Particular inhibition of NF-κB throughout peptide stimulation tuned the expression of early gene merchandise like c-Fos. Collectively, these knowledge point out a key function for ITK in orchestrating the optimum activation of separate TCR downstream pathways, particularly aiding NF-κB activation. Extra broadly, we revealed a mechanism by which variations in TCR sign energy can produce patterns of graded gene expression in activated T cells.
 Recombinant Mouse T Cell Immunoglobulin and Mucin Domain-3 Protein |
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MBS2556751-001mg |
MyBiosource |
0.01mg |
EUR 170 |
Recombinant Mouse T Cell Immunoglobulin and Mucin Domain-3 Protein |
|
MBS2556751-005mg |
MyBiosource |
0.05mg |
EUR 305 |
Recombinant Mouse T Cell Immunoglobulin and Mucin Domain-3 Protein |
|
MBS2556751-5x005mg |
MyBiosource |
5x0.05mg |
EUR 1365 |
 Antibody) Anti-Mouse T-cell Immunoglobulin Mucin-3 (TIM-3) Antibody |
|
103-M276 |
ReliaTech |
100 µg |
EUR 399 |
|
Description: T cell immunoglobulin mucin-3 (TIM-3) is a member of the T-cell Immunoglobulin- and Mucin-domain-containing family of type I membrane glycoproteins that regulate autoimmune and allergic disease. TIM-3 is selectively expressed on Th1 cells and interacts with galectin-9. It negatively regulates Th1 responses and affects macrophage activation. The 280 aa mature human TIM-3 contains a V-type Ig-like domain that shows multiple polymorphisms, followed by a mucin-like domain in the 171 aa extracellular region, which shares 60% amino acid identity with mouse TIM-3 ECD. One splice variant of TIM-3 is truncated within the mucin domain and presumably is secreted. |
) Recombinant Mouse T Cell Immunoglobulin and Mucin Domain-3/TIM-3/HAVCR2 (C-Fc) |
|
CM03-10ug |
Novoprotein |
10ug |
EUR 151.2 |
|
Description: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4. |
Recombinant Mouse T Cell Immunoglobulin and Mucin Domain-3/TIM-3/HAVCR2 (C-Fc) |
|
CM03-1mg |
Novoprotein |
1mg |
EUR 2252.4 |
|
Description: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4. |
Recombinant Mouse T Cell Immunoglobulin and Mucin Domain-3/TIM-3/HAVCR2 (C-Fc) |
|
CM03-500ug |
Novoprotein |
500ug |
EUR 1593.6 |
|
Description: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4. |
Recombinant Mouse T Cell Immunoglobulin and Mucin Domain-3/TIM-3/HAVCR2 (C-Fc) |
|
CM03-50ug |
Novoprotein |
50ug |
EUR 278.4 |
|
Description: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4. |
Recombinant Mouse T Cell Immunoglobulin and Mucin Domain-3/TIM-3/HAVCR2 (C-Fc) |
|
AP76216 |
SAB |
1mg |
EUR 2649 |
|
|
) Recombinant Mouse T cell Immunoglobulin and Mucin Domain-3/TIM-3/HAVCR2 (C-6His) |
|
CK57-10ug |
Novoprotein |
10ug |
EUR 132 |
|
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
Recombinant Mouse T cell Immunoglobulin and Mucin Domain-3/TIM-3/HAVCR2 (C-6His) |
|
CK57-1mg |
Novoprotein |
1mg |
EUR 2008.8 |
|
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
Recombinant Mouse T cell Immunoglobulin and Mucin Domain-3/TIM-3/HAVCR2 (C-6His) |
|
CK57-500ug |
Novoprotein |
500ug |
EUR 1423.2 |
|
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
Recombinant Mouse T cell Immunoglobulin and Mucin Domain-3/TIM-3/HAVCR2 (C-6His) |
|
CK57-50ug |
Novoprotein |
50ug |
EUR 278.4 |
|
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
) Recombinant Mouse T Cell Immunoglobulin and Mucin Domain-3/TIM-3/HAVCR2 (C-6His) |
|
CM54-10ug |
Novoprotein |
10ug |
EUR 151.2 |
|
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
Recombinant Mouse T Cell Immunoglobulin and Mucin Domain-3/TIM-3/HAVCR2 (C-6His) |
|
CM54-1mg |
Novoprotein |
1mg |
EUR 2252.4 |
|
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
Recombinant Mouse T Cell Immunoglobulin and Mucin Domain-3/TIM-3/HAVCR2 (C-6His) |
|
CM54-500ug |
Novoprotein |
500ug |
EUR 1593.6 |
|
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
Recombinant Mouse T Cell Immunoglobulin and Mucin Domain-3/TIM-3/HAVCR2 (C-6His) |
|
CM54-50ug |
Novoprotein |
50ug |
EUR 278.4 |
|
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
Recombinant Mouse T cell Immunoglobulin and Mucin Domain-3/TIM-3/HAVCR2 (C-6His) |
|
AP76176 |
SAB |
1mg |
EUR 2369 |
|
|
Recombinant Mouse T Cell Immunoglobulin and Mucin Domain-3/TIM-3/HAVCR2 (C-6His) |
|
AP76258 |
SAB |
1mg |
EUR 2649 |
|
|
 Antibody) Anti-Mouse T-cell Immunoglobulin Mucin-1 (TIM-1) Antibody |
|
103-M274 |
ReliaTech |
100 µg |
EUR 399 |
|
Description: MUC-1 (Mucin-1; also PEM, PEMT, Episialin, tumor-associated mucin, and carcinoma associated mucin) is a 240-450 kDa type I transmembrane glycoprotein. Human MUC-1 is 1255 amino acids (aa) in length and contains a 23 aa signal sequence, a 1135 aa extracellular domain (ECD), a 23 aa transmembrane segment, and a 74 aa cytoplasmic tail. The ECD consists of degenerate tandem repeats and a tandem repeat region, which makes up the major portion of the protein. Potential O-glycosylation sites (serines and threonines) make up more than one-fourth of the amino acids. Splicing variants produce ten isoforms for human MUC-1. Human MUC-1 is 28% aa identical to mouse MUC-1. |
 Antibody) Anti-Mouse T-cell Immunoglobulin Mucin-2 (TIM-2) Antibody |
|
103-M275 |
ReliaTech |
100 µg |
EUR 399 |
|
Description: TIM-2 is a type I membrane protein and is a member of the TIM protein family. TIM-2 has an immunoglobulin variable region-like domain followed by a mucin-like domain in its extracellular region.This protein family is characterized by their conserved immunoglobulin and mucin domains, as well as by their expression on activated T cells. TIM-2 is a receptor for Semaphorin 4A, which is expressed on dendritic cells and B cells. Semaphorin 4A has been shown to enhance T cell activation. |
 Antibody) T-Cell Immunoglobulin Mucin Receptor 3 (TIM3) Antibody |
|
20-abx225210 |
Abbexa |
-
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|
|
|
|
T-Cell Immunoglobulin Mucin Receptor 3 (TIM3) Antibody |
|
abx430303-200ul |
Abbexa |
200 ul |
EUR 460.8 |
|
|
 Antibody) T-Cell Immunoglobulin Mucin Receptor 3 (TIM-3) Antibody |
|
abx412054-01mg |
Abbexa |
0.1 mg |
EUR 844.8 |
|
|
T-Cell Immunoglobulin Mucin Receptor 3 (TIM-3) Antibody |
|
abx415211-05mg |
Abbexa |
0.5 mg |
EUR 994.8 |
|
|
T-Cell Immunoglobulin Mucin Receptor 3 (TIM-3) Antibody |
|
abx415213-01mg |
Abbexa |
0.1 mg |
EUR 526.8 |
|
|
 Antibody (RPE)) T-Cell Immunoglobulin Mucin Receptor 3 (TIM-3) Antibody (RPE) |
|
abx415214-100tests |
Abbexa |
100 tests |
EUR 710.4 |
|
|
 Antibody (FITC)) T-Cell Immunoglobulin Mucin Receptor 3 (TIM-3) Antibody (FITC) |
|
abx415212-01mg |
Abbexa |
0.1 mg |
EUR 610.8 |
|
|
 Antibody) Human T-Cell Immunoglobulin Mucin Receptor 3 (TIM-3) Antibody |
|
32146-05111 |
AssayPro |
150 ug |
EUR 215 |
 Mouse Solubility T Cell Immunoglobulin-and Mucin-Domain-Containing Molecule-3 ELISA Kit |
|
MBS3807468-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 6725 |
Mouse Solubility T Cell Immunoglobulin-and Mucin-Domain-Containing Molecule-3 ELISA Kit |
|
MBS3807468-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 550 |
Mouse Solubility T Cell Immunoglobulin-and Mucin-Domain-Containing Molecule-3 ELISA Kit |
|
MBS3807468-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 3420 |
Mouse Solubility T Cell Immunoglobulin-and Mucin-Domain-Containing Molecule-3 ELISA Kit |
|
MBS3807468-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 765 |
 (PE)) TIM-3 (Tim3, Timd3, T-cell Immunoglobulin Mucin 3, Havcr2) (PE) |
|
MBS6252228-01mL |
MyBiosource |
0.1(mL |
EUR 860 |
TIM-3 (Tim3, Timd3, T-cell Immunoglobulin Mucin 3, Havcr2) (PE) |
|
MBS6252228-5x01mL |
MyBiosource |
5x0.1mL |
EUR 3720 |
 (AP)) TIM-3 (Tim3, Timd3, T-cell Immunoglobulin Mucin 3, Havcr2) (AP) |
|
MBS6248357-01mL |
MyBiosource |
0.1(mL |
EUR 860 |
TIM-3 (Tim3, Timd3, T-cell Immunoglobulin Mucin 3, Havcr2) (AP) |
|
MBS6248357-5x01mL |
MyBiosource |
5x0.1mL |
EUR 3720 |
 (APC)) TIM-3 (Tim3, Timd3, T-cell Immunoglobulin Mucin 3, Havcr2) (APC) |
|
MBS6269209-01mL |
MyBiosource |
0.1mL |
EUR 860 |
TIM-3 (Tim3, Timd3, T-cell Immunoglobulin Mucin 3, Havcr2) (APC) |
|
MBS6269209-5x01mL |
MyBiosource |
5x0.1mL |
EUR 3720 |
 (HRP)) TIM-3 (Tim3, Timd3, T-cell Immunoglobulin Mucin 3, Havcr2) (HRP) |
|
MBS6251292-01mL |
MyBiosource |
0.1(mL |
EUR 860 |
TIM-3 (Tim3, Timd3, T-cell Immunoglobulin Mucin 3, Havcr2) (HRP) |
|
MBS6251292-5x01mL |
MyBiosource |
5x0.1mL |
EUR 3720 |
 (FITC)) TIM-3 (Tim3, Timd3, T-cell Immunoglobulin Mucin 3, Havcr2) (FITC) |
|
MBS6250265-01mL |
MyBiosource |
0.1(mL |
EUR 860 |
TIM-3 (Tim3, Timd3, T-cell Immunoglobulin Mucin 3, Havcr2) (FITC) |
|
MBS6250265-5x01mL |
MyBiosource |
5x0.1mL |
EUR 3720 |
 (Biotin)) TIM-3 (Tim3, Timd3, T-cell Immunoglobulin Mucin 3, Havcr2) (Biotin) |
|
MBS6249365-01mL |
MyBiosource |
0.1(mL |
EUR 860 |
TIM-3 (Tim3, Timd3, T-cell Immunoglobulin Mucin 3, Havcr2) (Biotin) |
|
MBS6249365-5x01mL |
MyBiosource |
5x0.1mL |
EUR 3720 |
 Antibody) T-Cell Immunoglobulin Mucin Receptor 1 (TIM-1) Antibody |
|
abx433377-100g |
Abbexa |
100 µg |
EUR 387.5 |
T-Cell Immunoglobulin Mucin Receptor 1 (TIM-1) Antibody |
|
abx433377-200ul |
Abbexa |
200 ul |
EUR 460.8 |
|
|
T-Cell Immunoglobulin Mucin Receptor 1 (TIM-1) Antibody |
|
abx375362-96tests |
Abbexa |
96 tests |
EUR 337.5 |
T-Cell Immunoglobulin Mucin Receptor 1 (TIM-1) Antibody |
|
abx411874-01mg |
Abbexa |
0.1 mg |
EUR 644.4 |
|
|
T-Cell Immunoglobulin Mucin Receptor 1 (TIM-1) Antibody |
|
abx411874-100g |
Abbexa |
100 µg |
EUR 437.5 |
 Antibody) T-Cell Immunoglobulin Mucin Receptor 4 (TIM-4) Antibody |
|
abx411875-01mg |
Abbexa |
0.1 mg |
EUR 661.2 |
|
|
T-Cell Immunoglobulin Mucin Receptor 4 (TIM-4) Antibody |
|
abx411875-100tests |
Abbexa |
100 tests |
EUR 450 |
T-Cell Immunoglobulin Mucin Receptor 1 (TIM-1) Antibody |
|
abx415204-05mg |
Abbexa |
0.5 mg |
EUR 994.8 |
|
|
T-Cell Immunoglobulin Mucin Receptor 1 (TIM-1) Antibody |
|
abx415206-01mg |
Abbexa |
0.1 mg |
EUR 526.8 |
|
|
T-Cell Immunoglobulin Mucin Receptor 1 (TIM-1) Antibody |
|
abx415206-200l |
Abbexa |
200 µl |
EUR 337.5 |
T-Cell Immunoglobulin Mucin Receptor 4 (TIM-4) Antibody |
|
abx415215-05mg |
Abbexa |
0.5 mg |
EUR 994.8 |
|
|
T-Cell Immunoglobulin Mucin Receptor 4 (TIM-4) Antibody |
|
abx415216-01mg |
Abbexa |
0.1 mg |
EUR 526.8 |
|
|
T-Cell Immunoglobulin Mucin Receptor 4 (TIM-4) Antibody |
|
abx415216-200l |
Abbexa |
200 µl |
EUR 337.5 |
 Antibody (PE)) T-Cell Immunoglobulin Mucin Receptor 1 (TIM-1) Antibody (PE) |
|
abx415207-200l |
Abbexa |
200 µl |
EUR 487.5 |
 (PE)) TIM-2 (T-cell Immunoglobulin Mucin 2, Timd2, Tim2) (PE) |
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MBS6252227-01mL |
MyBiosource |
0.1(mL |
EUR 860 |
TIM-2 (T-cell Immunoglobulin Mucin 2, Timd2, Tim2) (PE) |
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MBS6252227-5x01mL |
MyBiosource |
5x0.1mL |
EUR 3720 |
 (PE)) TIM-4 (T-cell Immunoglobulin Mucin 4, Tim4, Timd4) (PE) |
|
MBS6252229-01mL |
MyBiosource |
0.1(mL |
EUR 860 |
TIM-4 (T-cell Immunoglobulin Mucin 4, Tim4, Timd4) (PE) |
|
MBS6252229-5x01mL |
MyBiosource |
5x0.1mL |
EUR 3720 |
 (AP)) TIM-2 (T-cell Immunoglobulin Mucin 2, Timd2, Tim2) (AP) |
|
MBS6248356-01mL |
MyBiosource |
0.1(mL |
EUR 860 |
TIM-2 (T-cell Immunoglobulin Mucin 2, Timd2, Tim2) (AP) |
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MBS6248356-5x01mL |
MyBiosource |
5x0.1mL |
EUR 3720 |
 (AP)) TIM-4 (T-cell Immunoglobulin Mucin 4, Tim4, Timd4) (AP) |
|
MBS6248358-01mL |
MyBiosource |
0.1(mL |
EUR 860 |
TIM-4 (T-cell Immunoglobulin Mucin 4, Tim4, Timd4) (AP) |
|
MBS6248358-5x01mL |
MyBiosource |
5x0.1mL |
EUR 3720 |
 Antibody (RPE)) T-Cell Immunoglobulin Mucin Receptor 1 (TIM-1) Antibody (RPE) |
|
abx415207-100tests |
Abbexa |
100 tests |
EUR 710.4 |
|
|
 (MaxLight 405)) TIM-3 (Tim3, Timd3, T-cell Immunoglobulin Mucin 3, Havcr2) (MaxLight 405) |
|
MBS6253267-01mL |
MyBiosource |
0.1(mL |
EUR 860 |
TIM-3 (Tim3, Timd3, T-cell Immunoglobulin Mucin 3, Havcr2) (MaxLight 405) |
|
MBS6253267-5x01mL |
MyBiosource |
5x0.1mL |
EUR 3720 |
 (MaxLight 550)) TIM-3 (Tim3, Timd3, T-cell Immunoglobulin Mucin 3, Havcr2) (MaxLight 550) |
|
MBS6255347-01mL |
MyBiosource |
0.1(mL |
EUR 860 |
TIM-3 (Tim3, Timd3, T-cell Immunoglobulin Mucin 3, Havcr2) (MaxLight 550) |
|
MBS6255347-5x01mL |
MyBiosource |
5x0.1mL |
EUR 3720 |
 (MaxLight 650)) TIM-3 (Tim3, Timd3, T-cell Immunoglobulin Mucin 3, Havcr2) (MaxLight 650) |
|
MBS6256387-01mL |
MyBiosource |
0.1(mL |
EUR 860 |
TIM-3 (Tim3, Timd3, T-cell Immunoglobulin Mucin 3, Havcr2) (MaxLight 650) |
|
MBS6256387-5x01mL |
MyBiosource |
5x0.1mL |
EUR 3720 |
 (MaxLight 750)) TIM-3 (Tim3, Timd3, T-cell Immunoglobulin Mucin 3, Havcr2) (MaxLight 750) |
|
MBS6257426-01mL |
MyBiosource |
0.1mL |
EUR 860 |
TIM-3 (Tim3, Timd3, T-cell Immunoglobulin Mucin 3, Havcr2) (MaxLight 750) |
|
MBS6257426-5x01mL |
MyBiosource |
5x0.1mL |
EUR 3720 |
 (MaxLight 490)) TIM-3 (Tim3, Timd3, T-cell Immunoglobulin Mucin 3, Havcr2) (MaxLight 490) |
|
MBS6254307-01mL |
MyBiosource |
0.1(mL |
EUR 860 |
TIM-3 (Tim3, Timd3, T-cell Immunoglobulin Mucin 3, Havcr2) (MaxLight 490) |
|
MBS6254307-5x01mL |
MyBiosource |
5x0.1mL |
EUR 3720 |
 (APC)) TIM-2 (T-cell Immunoglobulin Mucin 2, Timd2, Tim2) (APC) |
|
MBS6269208-01mL |
MyBiosource |
0.1mL |
EUR 860 |
TIM-2 (T-cell Immunoglobulin Mucin 2, Timd2, Tim2) (APC) |
|
MBS6269208-5x01mL |
MyBiosource |
5x0.1mL |
EUR 3720 |
 (APC)) TIM-4 (T-cell Immunoglobulin Mucin 4, Tim4, Timd4) (APC) |
|
MBS6269210-01mL |
MyBiosource |
0.1mL |
EUR 860 |
TIM-4 (T-cell Immunoglobulin Mucin 4, Tim4, Timd4) (APC) |
|
MBS6269210-5x01mL |
MyBiosource |
5x0.1mL |
EUR 3720 |
 (HRP)) TIM-2 (T-cell Immunoglobulin Mucin 2, Timd2, Tim2) (HRP) |
|
MBS6251291-01mL |
MyBiosource |
0.1(mL |
EUR 860 |
TIM-2 (T-cell Immunoglobulin Mucin 2, Timd2, Tim2) (HRP) |
|
MBS6251291-5x01mL |
MyBiosource |
5x0.1mL |
EUR 3720 |
 (HRP)) TIM-4 (T-cell Immunoglobulin Mucin 4, Tim4, Timd4) (HRP) |
|
MBS6251293-01mL |
MyBiosource |
0.1(mL |
EUR 860 |
TIM-4 (T-cell Immunoglobulin Mucin 4, Tim4, Timd4) (HRP) |
|
MBS6251293-5x01mL |
MyBiosource |
5x0.1mL |
EUR 3720 |
) Tim3 (T Cell Immunoglobulin and Mucin Domain-containing 3, T Cell Immunoglobulin Mucin 3, TIM3, TIM-3, TIMD3, FLJ14428, Hepatitis A Virus Cellular Receptor 2, HAVCR 2, HAVCR2, HAVCR-2, Kidney Injury Molecule 3, KIM-3) |
|
MBS620755-01mg |
MyBiosource |
0.1mg |
EUR 810 |
Tim3 (T Cell Immunoglobulin and Mucin Domain-containing 3, T Cell Immunoglobulin Mucin 3, TIM3, TIM-3, TIMD3, FLJ14428, Hepatitis A Virus Cellular Receptor 2, HAVCR 2, HAVCR2, HAVCR-2, Kidney Injury Molecule 3, KIM-3) |
|
MBS620755-5x01mg |
MyBiosource |
5x0.1mg |
EUR 3500 |
) TIM3 (T Cell Immunoglobulin and Mucin Domain-containing 3, T Cell Immunoglobulin Mucin 3, TIM3, TIM-3, TIMD3, FLJ14428, Hepatitis A Virus Cellular Receptor 2, HAVCR 2, HAVCR2, HAVCR-2, Kidney Injury Molecule 3, KIM-3) |
|
MBS6506798-01mL |
MyBiosource |
0.1mL |
EUR 715 |
TIM3 (T Cell Immunoglobulin and Mucin Domain-containing 3, T Cell Immunoglobulin Mucin 3, TIM3, TIM-3, TIMD3, FLJ14428, Hepatitis A Virus Cellular Receptor 2, HAVCR 2, HAVCR2, HAVCR-2, Kidney Injury Molecule 3, KIM-3) |
|
MBS6506798-5x01mL |
MyBiosource |
5x0.1mL |
EUR 3075 |
 Antibody (FITC)) T-Cell Immunoglobulin Mucin Receptor 1 (TIM-1) Antibody (FITC) |
|
abx415205-01mg |
Abbexa |
0.1 mg |
EUR 610.8 |
|
|
T-Cell Immunoglobulin Mucin Receptor 1 (TIM-1) Antibody (FITC) |
|
abx415205-200l |
Abbexa |
200 µl |
EUR 400 |
 (FITC)) TIM-2 (T-cell Immunoglobulin Mucin 2, Timd2, Tim2) (FITC) |
|
MBS6250264-01mL |
MyBiosource |
0.1(mL |
EUR 860 |
TIM-2 (T-cell Immunoglobulin Mucin 2, Timd2, Tim2) (FITC) |
|
MBS6250264-5x01mL |
MyBiosource |
5x0.1mL |
EUR 3720 |
 (FITC)) TIM-4 (T-cell Immunoglobulin Mucin 4, Tim4, Timd4) (FITC) |
|
MBS6250266-01mL |
MyBiosource |
0.1(mL |
EUR 860 |
TIM-4 (T-cell Immunoglobulin Mucin 4, Tim4, Timd4) (FITC) |
|
MBS6250266-5x01mL |
MyBiosource |
5x0.1mL |
EUR 3720 |
 Mouse T-Cell Immunoglobulin and Mucin Domain Containing Protein 4 ELISA Kit |
|
MBS069521-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 6725 |
Mouse T-Cell Immunoglobulin and Mucin Domain Containing Protein 4 ELISA Kit |
|
MBS069521-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 550 |
Mouse T-Cell Immunoglobulin and Mucin Domain Containing Protein 4 ELISA Kit |
|
MBS069521-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 3420 |
Mouse T-Cell Immunoglobulin and Mucin Domain Containing Protein 4 ELISA Kit |
|
MBS069521-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 765 |
) Recombinant Human T Cell Immunoglobulin and Mucin Domain-3/TIM3/HAVCR2 (C-6His) |
|
C356-10ug |
Novoprotein |
10ug |
EUR 145.2 |
|
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2. |
Recombinant Human T Cell Immunoglobulin and Mucin Domain-3/TIM3/HAVCR2 (C-6His) |
|
C356-1mg |
Novoprotein |
1mg |
EUR 2739.6 |
|
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2. |
Recombinant Human T Cell Immunoglobulin and Mucin Domain-3/TIM3/HAVCR2 (C-6His) |
|
C356-500ug |
Novoprotein |
500ug |
EUR 1935.6 |
|
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2. |
Recombinant Human T Cell Immunoglobulin and Mucin Domain-3/TIM3/HAVCR2 (C-6His) |
|
C356-50ug |
Novoprotein |
50ug |
EUR 315.6 |
|
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2. |
Recombinant Human T Cell Immunoglobulin and Mucin Domain-3/TIM3/HAVCR2 (C-6His) |
|
AP75076 |
SAB |
1mg |
EUR 3209 |
|
|
 (APC)) TIM3 (T Cell Immunoglobulin and Mucin Domain-containing 3, T Cell Immunoglobulin Mucin 3, TIM3, TIM-3, TIMD3, FLJ14428, Hepatitis A Virus Cellular Receptor 2, HAVCR 2, HAVCR2, HAVCR-2, Kidney Injury Molecule 3, KIM-3) (APC) |
|
MBS6242532-01mL |
MyBiosource |
0.1(mL |
EUR 1005 |
TIM3 (T Cell Immunoglobulin and Mucin Domain-containing 3, T Cell Immunoglobulin Mucin 3, TIM3, TIM-3, TIMD3, FLJ14428, Hepatitis A Virus Cellular Receptor 2, HAVCR 2, HAVCR2, HAVCR-2, Kidney Injury Molecule 3, KIM-3) (APC) |
|
MBS6242532-5x01mL |
MyBiosource |
5x0.1mL |
EUR 4375 |
 (Biotin)) TIM3 (T Cell Immunoglobulin and Mucin Domain-containing 3, T Cell Immunoglobulin Mucin 3, TIM3, TIM-3, TIMD3, FLJ14428, Hepatitis A Virus Cellular Receptor 2, HAVCR 2, HAVCR2, HAVCR-2, Kidney Injury Molecule 3, KIM-3) (Biotin) |
|
MBS6243064-01mL |
MyBiosource |
0.1(mL |
EUR 1005 |
TIM3 (T Cell Immunoglobulin and Mucin Domain-containing 3, T Cell Immunoglobulin Mucin 3, TIM3, TIM-3, TIMD3, FLJ14428, Hepatitis A Virus Cellular Receptor 2, HAVCR 2, HAVCR2, HAVCR-2, Kidney Injury Molecule 3, KIM-3) (Biotin) |
|
MBS6243064-5x01mL |
MyBiosource |
5x0.1mL |
EUR 4375 |
 (FITC)) TIM3 (T Cell Immunoglobulin and Mucin Domain-containing 3, T Cell Immunoglobulin Mucin 3, TIM3, TIM-3, TIMD3, FLJ14428, Hepatitis A Virus Cellular Receptor 2, HAVCR 2, HAVCR2, HAVCR-2, Kidney Injury Molecule 3, KIM-3) (FITC) |
|
MBS6243597-01mL |
MyBiosource |
0.1(mL |
EUR 1005 |
TIM3 (T Cell Immunoglobulin and Mucin Domain-containing 3, T Cell Immunoglobulin Mucin 3, TIM3, TIM-3, TIMD3, FLJ14428, Hepatitis A Virus Cellular Receptor 2, HAVCR 2, HAVCR2, HAVCR-2, Kidney Injury Molecule 3, KIM-3) (FITC) |
|
MBS6243597-5x01mL |
MyBiosource |
5x0.1mL |
EUR 4375 |
 (HRP)) TIM3 (T Cell Immunoglobulin and Mucin Domain-containing 3, T Cell Immunoglobulin Mucin 3, TIM3, TIM-3, TIMD3, FLJ14428, Hepatitis A Virus Cellular Receptor 2, HAVCR 2, HAVCR2, HAVCR-2, Kidney Injury Molecule 3, KIM-3) (HRP) |
|
MBS6244130-01mL |
MyBiosource |
0.1(mL |
EUR 1005 |
TIM3 (T Cell Immunoglobulin and Mucin Domain-containing 3, T Cell Immunoglobulin Mucin 3, TIM3, TIM-3, TIMD3, FLJ14428, Hepatitis A Virus Cellular Receptor 2, HAVCR 2, HAVCR2, HAVCR-2, Kidney Injury Molecule 3, KIM-3) (HRP) |
|
MBS6244130-5x01mL |
MyBiosource |
5x0.1mL |
EUR 4375 |
 (PE)) TIM3 (T Cell Immunoglobulin and Mucin Domain-containing 3, T Cell Immunoglobulin Mucin 3, TIM3, TIM-3, TIMD3, FLJ14428, Hepatitis A Virus Cellular Receptor 2, HAVCR 2, HAVCR2, HAVCR-2, Kidney Injury Molecule 3, KIM-3) (PE) |
|
MBS6244663-01mL |
MyBiosource |
0.1(mL |
EUR 1005 |
TIM3 (T Cell Immunoglobulin and Mucin Domain-containing 3, T Cell Immunoglobulin Mucin 3, TIM3, TIM-3, TIMD3, FLJ14428, Hepatitis A Virus Cellular Receptor 2, HAVCR 2, HAVCR2, HAVCR-2, Kidney Injury Molecule 3, KIM-3) (PE) |
|
MBS6244663-5x01mL |
MyBiosource |
5x0.1mL |
EUR 4375 |
 (AP)) TIM3 (T Cell Immunoglobulin and Mucin Domain-containing 3, T Cell Immunoglobulin Mucin 3, TIM3, TIM-3, TIMD3, FLJ14428, Hepatitis A Virus Cellular Receptor 2, HAVCR 2, HAVCR2, HAVCR-2, Kidney Injury Molecule 3, KIM-3) (AP) |
|
MBS6241999-01mL |
MyBiosource |
0.1(mL |
EUR 1005 |
TIM3 (T Cell Immunoglobulin and Mucin Domain-containing 3, T Cell Immunoglobulin Mucin 3, TIM3, TIM-3, TIMD3, FLJ14428, Hepatitis A Virus Cellular Receptor 2, HAVCR 2, HAVCR2, HAVCR-2, Kidney Injury Molecule 3, KIM-3) (AP) |
|
MBS6241999-5x01mL |
MyBiosource |
5x0.1mL |
EUR 4375 |
 (APC)) Tim3 (T Cell Immunoglobulin and Mucin Domain-containing 3, T Cell Immunoglobulin Mucin 3, TIM3, TIM-3, TIMD3, FLJ14428, Hepatitis A Virus Cellular Receptor 2, HAVCR 2, HAVCR2, HAVCR-2, Kidney Injury Molecule 3, KIM-3) (APC) |
|
MBS606914-100Tests |
MyBiosource |
100Tests |
EUR 935 |
Tim3 (T Cell Immunoglobulin and Mucin Domain-containing 3, T Cell Immunoglobulin Mucin 3, TIM3, TIM-3, TIMD3, FLJ14428, Hepatitis A Virus Cellular Receptor 2, HAVCR 2, HAVCR2, HAVCR-2, Kidney Injury Molecule 3, KIM-3) (APC) |
|
MBS606914-5x100Tests |
MyBiosource |
5x100Tests |
EUR 4050 |
 Antibody (Biotin Conjugate)) Human T-Cell Immunoglobulin Mucin Receptor 3 (TIM-3) Antibody (Biotin Conjugate) |
|
32146-05121 |
AssayPro |
150 ug |
EUR 315 |
 (Biotin)) TIM-2 (T-cell Immunoglobulin Mucin 2, Timd2, Tim2) (Biotin) |
|
MBS6249364-01mL |
MyBiosource |
0.1(mL |
EUR 860 |
TIM-2 (T-cell Immunoglobulin Mucin 2, Timd2, Tim2) (Biotin) |
|
MBS6249364-5x01mL |
MyBiosource |
5x0.1mL |
EUR 3720 |
 (Biotin)) TIM-4 (T-cell Immunoglobulin Mucin 4, Tim4, Timd4) (Biotin) |
|
MBS6249366-01mL |
MyBiosource |
0.1(mL |
EUR 860 |
TIM-4 (T-cell Immunoglobulin Mucin 4, Tim4, Timd4) (Biotin) |
|
MBS6249366-5x01mL |
MyBiosource |
5x0.1mL |
EUR 3720 |
 ELISA Kit) Human T cell immunoglobulin and mucin domain-containing protein 3 (TIM3) ELISA Kit |
|
SL3234Hu |
Sunlong |
96 Tests |
EUR 468 |
|
|
 Mouse T-cell immunoglobulin and mucin domain-containing protein 4 ELISA kit |
|
E03T0955-48wellsplate |
BlueGene |
48 wells plate |
EUR 280 |
Mouse T-cell immunoglobulin and mucin domain-containing protein 4 ELISA kit |
|
E03T0955-96wellsplate |
BlueGene |
96 wells plate |
EUR 405 |
 (MaxLight 405)) TIM3 (T Cell Immunoglobulin and Mucin Domain-containing 3, T Cell Immunoglobulin Mucin 3, TIM3, TIM-3, TIMD3, FLJ14428, Hepatitis A Virus Cellular Receptor 2, HAVCR 2, HAVCR2, HAVCR-2, Kidney Injury Molecule 3, KIM-3) (MaxLight 405) |
|
MBS6245196-01mL |
MyBiosource |
0.1(mL |
EUR 1005 |
TIM3 (T Cell Immunoglobulin and Mucin Domain-containing 3, T Cell Immunoglobulin Mucin 3, TIM3, TIM-3, TIMD3, FLJ14428, Hepatitis A Virus Cellular Receptor 2, HAVCR 2, HAVCR2, HAVCR-2, Kidney Injury Molecule 3, KIM-3) (MaxLight 405) |
|
MBS6245196-5x01mL |
MyBiosource |
5x0.1mL |
EUR 4375 |
 (MaxLight 490)) TIM3 (T Cell Immunoglobulin and Mucin Domain-containing 3, T Cell Immunoglobulin Mucin 3, TIM3, TIM-3, TIMD3, FLJ14428, Hepatitis A Virus Cellular Receptor 2, HAVCR 2, HAVCR2, HAVCR-2, Kidney Injury Molecule 3, KIM-3) (MaxLight 490) |
|
MBS6245729-01mL |
MyBiosource |
0.1(mL |
EUR 1005 |
TIM3 (T Cell Immunoglobulin and Mucin Domain-containing 3, T Cell Immunoglobulin Mucin 3, TIM3, TIM-3, TIMD3, FLJ14428, Hepatitis A Virus Cellular Receptor 2, HAVCR 2, HAVCR2, HAVCR-2, Kidney Injury Molecule 3, KIM-3) (MaxLight 490) |
|
MBS6245729-5x01mL |
MyBiosource |
5x0.1mL |
EUR 4375 |
 (MaxLight 550)) TIM3 (T Cell Immunoglobulin and Mucin Domain-containing 3, T Cell Immunoglobulin Mucin 3, TIM3, TIM-3, TIMD3, FLJ14428, Hepatitis A Virus Cellular Receptor 2, HAVCR 2, HAVCR2, HAVCR-2, Kidney Injury Molecule 3, KIM-3) (MaxLight 550) |
|
MBS6246262-01mL |
MyBiosource |
0.1(mL |
EUR 1005 |
TIM3 (T Cell Immunoglobulin and Mucin Domain-containing 3, T Cell Immunoglobulin Mucin 3, TIM3, TIM-3, TIMD3, FLJ14428, Hepatitis A Virus Cellular Receptor 2, HAVCR 2, HAVCR2, HAVCR-2, Kidney Injury Molecule 3, KIM-3) (MaxLight 550) |
|
MBS6246262-5x01mL |
MyBiosource |
5x0.1mL |
EUR 4375 |
 (MaxLight 650)) TIM3 (T Cell Immunoglobulin and Mucin Domain-containing 3, T Cell Immunoglobulin Mucin 3, TIM3, TIM-3, TIMD3, FLJ14428, Hepatitis A Virus Cellular Receptor 2, HAVCR 2, HAVCR2, HAVCR-2, Kidney Injury Molecule 3, KIM-3) (MaxLight 650) |
|
MBS6246795-01mL |
MyBiosource |
0.1(mL |
EUR 1005 |
TIM3 (T Cell Immunoglobulin and Mucin Domain-containing 3, T Cell Immunoglobulin Mucin 3, TIM3, TIM-3, TIMD3, FLJ14428, Hepatitis A Virus Cellular Receptor 2, HAVCR 2, HAVCR2, HAVCR-2, Kidney Injury Molecule 3, KIM-3) (MaxLight 650) |
|
MBS6246795-5x01mL |
MyBiosource |
5x0.1mL |
EUR 4375 |
 (MaxLight 750)) TIM3 (T Cell Immunoglobulin and Mucin Domain-containing 3, T Cell Immunoglobulin Mucin 3, TIM3, TIM-3, TIMD3, FLJ14428, Hepatitis A Virus Cellular Receptor 2, HAVCR 2, HAVCR2, HAVCR-2, Kidney Injury Molecule 3, KIM-3) (MaxLight 750) |
|
MBS6247328-01mL |
MyBiosource |
0.1(mL |
EUR 1005 |
TIM3 (T Cell Immunoglobulin and Mucin Domain-containing 3, T Cell Immunoglobulin Mucin 3, TIM3, TIM-3, TIMD3, FLJ14428, Hepatitis A Virus Cellular Receptor 2, HAVCR 2, HAVCR2, HAVCR-2, Kidney Injury Molecule 3, KIM-3) (MaxLight 750) |
|
MBS6247328-5x01mL |
MyBiosource |
5x0.1mL |
EUR 4375 |
antibody) T-cell immunoglobulin and mucin domain 1( TIM-1)antibody |
|
NBP0210-1 |
Bioworld Biotech |
each |
Ask for price |
|
|
|
Description: LF EIA,CLIA |
T-cell immunoglobulin and mucin domain 1( TIM-1)antibody |
|
NBP0210-2 |
Bioworld Biotech |
each |
Ask for price |
|
|
|
Description: LF EIA,CLIA |
 Human T Lymphocyte Immunoglobulin mucin 3,TIM-3 ELISA KIT |
|
JOT-EK7264Hu |
Jotbody |
96 wells |
Ask for price |
|
Description: Human |
 Human T Lymphocyte Immunoglobulin mucin 3, TIM-3 ELISA Kit |
|
MBS1608155-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 3460 |
Human T Lymphocyte Immunoglobulin mucin 3, TIM-3 ELISA Kit |
|
MBS1608155-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 285 |
Human T Lymphocyte Immunoglobulin mucin 3, TIM-3 ELISA Kit |
|
MBS1608155-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 1750 |
Human T Lymphocyte Immunoglobulin mucin 3, TIM-3 ELISA Kit |
|
MBS1608155-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 425 |
 Protein) Mouse T-Cell Immunoglobulin And Mucin Domain Containing Protein 4 (TIMD4) Protein |
|
abx692171-100g |
Abbexa |
100 µg |
EUR 837.5 |
Mouse T-Cell Immunoglobulin And Mucin Domain Containing Protein 4 (TIMD4) Protein |
|
abx692171-1mg |
Abbexa |
1 mg |
Ask for price |
) Recombinant Human T Cell Immunoglobulin and Mucin Domain-3/TIM-3/HAVCR2 (C-Fc-6His) |
|
CX71-10ug |
Novoprotein |
10ug |
EUR 145.2 |
|
Description: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4. |
Recombinant Human T Cell Immunoglobulin and Mucin Domain-3/TIM-3/HAVCR2 (C-Fc-6His) |
|
CX71-1mg |
Novoprotein |
1mg |
EUR 2739.6 |
|
Description: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4. |
Recombinant Human T Cell Immunoglobulin and Mucin Domain-3/TIM-3/HAVCR2 (C-Fc-6His) |
|
CX71-500ug |
Novoprotein |
500ug |
EUR 1935.6 |
|
Description: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4. |
Recombinant Human T Cell Immunoglobulin and Mucin Domain-3/TIM-3/HAVCR2 (C-Fc-6His) |
|
CX71-50ug |
Novoprotein |
50ug |
EUR 315.6 |
|
Description: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4. |
Recombinant Human T Cell Immunoglobulin and Mucin Domain-3/TIM-3/HAVCR2 (C-Fc-6His) |
|
AP75656 |
SAB |
1mg |
EUR 3209 |
|
|
 Mouse Hepatitis A virus cellular receptor 2/T-cell immunoglobulin and mucin-domain containing-3 ELISA kit |
|
E01A22718 |
BlueGene |
96T |
EUR 700 |
|
Description: ELISA |
Mouse Hepatitis A virus cellular receptor 2/T-cell immunoglobulin and mucin-domain containing-3 ELISA kit |
|
E03H1483-48wellsplate |
BlueGene |
48 wells plate |
EUR 280 |
Mouse Hepatitis A virus cellular receptor 2/T-cell immunoglobulin and mucin-domain containing-3 ELISA kit |
|
E03H1483-96wellsplate |
BlueGene |
96 wells plate |
EUR 405 |
 ELISA Kit) Mouse T-Cell Immunoglobulin And Mucin Domain Containing Protein 4 (TIMD4) ELISA Kit |
|
abx549775-96tests |
Abbexa |
96 tests |
EUR 687.5 |
Mouse T-Cell Immunoglobulin And Mucin Domain Containing Protein 4 (TIMD4) ELISA Kit |
|
EKU11802-48T |
Biomatik Corporation |
48T |
EUR 571.55 |
Mouse T-Cell Immunoglobulin And Mucin Domain Containing Protein 4 (TIMD4) ELISA Kit |
|
EKU11802-5x96T |
Biomatik Corporation |
5x96T |
EUR 3878.38 |
Mouse T-Cell Immunoglobulin And Mucin Domain Containing Protein 4 (TIMD4) ELISA Kit |
|
EKU11802-96T |
Biomatik Corporation |
96T |
EUR 816.5 |
Mouse T-Cell Immunoglobulin And Mucin Domain Containing Protein 4 (TIMD4) ELISA Kit |
|
EKN52913-48T |
Biomatik Corporation |
48T |
EUR 355.6 |
Mouse T-Cell Immunoglobulin And Mucin Domain Containing Protein 4 (TIMD4) ELISA Kit |
|
EKN52913-5x96T |
Biomatik Corporation |
5x96T |
EUR 2413 |
The neurobiology of schizophrenia is multifactorial, comprising the dysregulation of a number of biochemical pathways and molecules. This analysis proposes a peripheral biomarker for schizophrenia that includes the second extracellular loop of norepinephrine transporter (NEText), the tropomyosin receptor kinase C (TrkC), and the neurotrophin-3 (NT-3) in T cells. The examine of NEText, NT-3, and TrkC was carried out in T cells and plasma extracted from peripheral blood of 54 sufferers with schizophrenia and 54 wholesome controls
